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Nat Med 23:13621368 Saigusa D, Motoike IN, Saito S, Zorzi M, Aoki Y, Kitamura H, Suzuki M, Katsuoka F, Ishii H, Kinoshita K, Motohashi H, Yamamoto M (2019) Impacts of NRF2 activation in non-small-cell lung cancer cell lines on extracellular metabolites

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Additionally, OPCs are particularly susceptible to damage by oxidizing agents because of a delay in the production or reduced activity of antioxidant enzymes (e.g., glutathione peroxidase), which increases with maturation (Back et al., 1998